In a study, patients with irritable bowel syndrome with diarrhea, or IBS-D, who went on a low FODMAP diet saw an improvement of colonic barrier dysfunction, commonly known as “leaky gut.”
The results, published in Gastroenterology, represent the first evidence of low FODMAP’s potential ability to improve intestinal permeability and mast cell activation in patients with IBS.
Diet and microbiome have been believed to be related to leaky gut, but the reasons why were not well understood.
This research illuminates the mechanism of how food can interact with gut microbiome and gut immune system to influence colonic barrier dysfunction-and validates the low FODMAP diet as a treatment option that not only improves symptoms but…
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