Creatine may enhance neuroprotection through energy pathways

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Scientists reveal how creatine could do more than build muscle, fueling brain resilience, enhancing mood, and supporting cognitive performance through exercise-driven biochemical pathways.

Creatine powder text font on grey stone background with plastic spoon cupStudy: Creatine supplementation and muscle-brain axis: a new possible mechanism? Image credit: Sonis Photography/Shutterstock.com

Creatine supplementation is widely acknowledged for boosting muscular mass and strength and improving exercise performance. A recent review in Frontiers in Nutrition examined its impact on brain and muscle health via the muscle-brain axis.

Introduction 

Both the brain and skeletal muscle consume vast amounts of energy during activity. Creatine is a key regulatory molecule in both organ systems, preventing damage…



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