Gut hormone INSL5 linked to chronic diarrhea in patients with bile acid malabsorption

1753832437 Hormone



Hormone

High levels of a hormone found in cells in the gut could underlie many cases of chronic diarrhea and help explain up to 40% of cases of patients with irritable bowel syndrome with diarrhea, according to a new study led by scientists at the University of Cambridge.

The research, published in the journal Gut, could help in the development of a blood test and points towards a potential new treatment.

When we eat, the liver releases bile acid to break down fats so that they can be absorbed into the body. Bile acid is released into the top end of the small intestine and then absorbed back into the body at the lower end.

However, around one person in every 100 is affected by a condition known as bile acid diarrhea (also known as bile…



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